Marasa lafiya da ke fama da gazawar koda na buƙatar dialysis na yau da kullun, wanda ke da haɗari kuma mai yuwuwar magani.Amma yanzu masu bincike a Jami'ar California, San Francisco (UCSF) sun sami nasarar nuna wani samfurin koda na bioartificial wanda za'a iya dasa shi da aiki ba tare da buƙatar magunguna ba.
Koda tana aiwatar da ayyuka masu mahimmanci a cikin jiki, wanda ya fi shahara shi ne tace gubobi da abubuwan da ba su da amfani a cikin jini, sannan kuma suna daidaita hawan jini, tattarawar electrolyte da sauran ruwan jiki.
Don haka, lokacin da waɗannan gabobin suka fara gazawa, yana da wahala sosai don maimaita waɗannan hanyoyin.Yawancin lokaci marasa lafiya suna farawa da dialysis, amma wannan yana ɗaukar lokaci kuma yana da daɗi.Magani na dogon lokaci shine dashen koda, wanda zai iya dawo da mafi kyawun rayuwa, amma yana tare da buƙatar amfani da magungunan rigakafi don hana haɗari masu haɗari na ƙin yarda.
Don aikin koda na UCSF, ƙungiyar ta haɓaka ƙwayar ƙwayar ƙwayar cuta wanda za'a iya dasa shi a cikin marasa lafiya don yin manyan ayyuka na ainihin abubuwa, amma baya buƙatar magungunan rigakafi ko magungunan jini, wanda ake buƙata sau da yawa.
Na'urar ta ƙunshi manyan sassa biyu.Tacewar jini yana kunshe da membrane semiconductor na silicon, wanda zai iya cire sharar gida daga cikin jini.A lokaci guda kuma, bioreactor yana ƙunshe da sel tubular renal injiniyoyi waɗanda zasu iya daidaita girman ruwa, ma'aunin electrolyte da sauran ayyukan rayuwa.Har ila yau, membrane yana kare waɗannan ƙwayoyin cuta daga harin da tsarin rigakafi na majiyyaci.
Gwaje-gwajen da aka yi a baya sun ba kowane ɗayan waɗannan kayan aikin damar yin aiki da kansa, amma wannan shine karo na farko da ƙungiyar ta gwada su don yin aiki tare a cikin na'ura.
Kodar bioartificial tana da alaƙa da manyan jijiyoyin jini guda biyu a jikin majinyaci – ɗaya yana ɗaukar jinin da aka tace a cikin jiki ɗayan kuma yana ɗaukar jinin da aka tace ya koma cikin jiki – kuma zuwa mafitsara, inda sharar ta kasance a cikin hanyar fitsari.
A halin yanzu ƙungiyar ta gudanar da gwajin hujja, wanda ke nuna cewa koda bioartificial yana aiki ne kawai a ƙarƙashin hawan jini kuma baya buƙatar famfo ko tushen wutar lantarki na waje.Kwayoyin tubular na koda suna rayuwa kuma suna ci gaba da aiki a duk lokacin gwajin.
Godiya ga kokarin da suka yi, masu bincike a Jami'ar California, San Francisco yanzu sun sami kyautar KidneyX $ 650,000 a matsayin daya daga cikin wadanda suka lashe kashi na farko na kyautar koda na wucin gadi.
Shuvo Roy, jagorar mai binciken aikin, ya ce: "Tawagarmu ta tsara wata koda ta wucin gadi wacce za ta iya ci gaba da tallafawa noman ƙwayoyin koda na ɗan adam ba tare da haifar da martanin rigakafi ba."Tare da yuwuwar haɗuwar reactor, za mu iya mai da hankali kan haɓaka fasahar don ƙarin tsauraran gwaji kafin asibiti da kuma gwaji na asibiti a ƙarshe. ”