Masu bincike daga Sashen Injiniyan Injiniya da Aerospace Engineering (MAE) na Makarantar Injiniya ta Herbert Wertheim sun haɓaka sabon nau'in membrane na hemodialysis wanda aka yi da graphene oxide (GO), wanda wani abu ne mai launi na monoatomic.Ana sa ran za a canza gaba daya maganin dialysis na koda cikin haƙuri.Wannan ci gaban yana ba da damar maƙala microchip dializer zuwa fatar mara lafiya.Yin aiki a ƙarƙashin matsa lamba na jijiya, zai kawar da bugun jini da kewayen jini na waje, yana ba da damar lafiyan dialysis a cikin kwanciyar hankali na gidan ku.Idan aka kwatanta da ɓangarorin polymer ɗin da ke akwai, daɗaɗɗen membrane shine umarni biyu na girma mafi girma, yana da karfin jini, kuma ba shi da sauƙi a sikelin kamar membran polymer.
Farfesa Knox T. Millsaps na MAE da kuma jagoran bincike na aikin membrane Saeed Moghaddam da tawagarsa sun kirkiro wani sabon tsari wanda ya shafi hada kai da inganta yanayin jiki da sinadarai na GO nanoplatelets.Wannan tsari kawai yana juyar da yadudduka na 3 GO zuwa manyan taruka na nanosheet, ta yadda za'a cimma matsaya mai ƙarfi da zaɓi."Ta hanyar haɓaka membrane wanda ya fi dacewa fiye da takwarorinsa na halitta, membrane glomerular basement membrane (GBM) na koda, mun nuna babban yuwuwar nanomaterials, nanoengineering, da haɗin kai na kwayoyin."Mogda Dr. Mu ce.
Nazarin aikin membrane a cikin yanayin hemodialysis ya haifar da sakamako mai ƙarfafawa sosai.Matsakaicin adadin urea da cytochrome-c sune 0.5 da 0.4, bi da bi, waɗanda suka isa don jinkirin dialysis na dogon lokaci yayin da suke riƙe fiye da 99% na albumin;Nazarin kan hemolysis, haɓaka haɓakawa da coagulation sun nuna cewa sun yi daidai da kayan membrane na dialysis na yanzu Ko mafi kyau fiye da aikin kayan membrane na dialysis na yanzu.Sakamakon wannan binciken an buga shi akan manyan Mu'amalar Materials (Fabrairu 5, 2021) ƙarƙashin taken "Trilayer Interlinked Graphene Oxide Membrane for Wearable Hemodialyzer".
Dr. Moghaddam ya ce: "Mun nuna wani tsari na musamman na GO nanoplatelet wanda ya ba da umarnin mosaic, wanda ke inganta kokarin da aka yi na tsawon shekaru goma wajen samar da membranes na graphene."Yana da wani dandali mai amfani wanda zai iya haɓaka ƙananan ƙwayoyin cuta na dare a gida. "A halin yanzu Dr. Moghaddam yana aiki a kan samar da microchips ta hanyar amfani da sababbin GO membranes, wanda zai kawo bincike kusa da gaskiyar samar da kayan aikin hemodialysis na sawa ga masu ciwon koda.
Edita na Nature (Maris 2020) ya ce: “Hukumar Lafiya ta Duniya ta ƙiyasta cewa kusan mutane miliyan 1.2 ne ke mutuwa saboda gazawar koda a duk shekara a duk duniya [da kuma cutar da cutar renal ta ƙarshe (ESRD) na faruwa ne saboda ciwon sukari da hauhawar jini]….Dialysis Haɗin ƙarancin fasaha na fasaha da araha kuma yana nufin cewa ƙasa da rabin mutanen da ke buƙatar magani suna samun damar yin amfani da shi.Ƙananan na'urori masu sawa da suka dace, mafita ce ta tattalin arziki don haɓaka ƙimar rayuwa, musamman a cikin ci gaban kasar Sin.Dokta Moghaddam ya ce "Maɓallin mu shine maɓalli mai mahimmanci na ƙaramin tsarin sawa, wanda zai iya haifar da aikin tacewa na koda, yana inganta jin dadi da araha a duk duniya," in ji Dokta Moghaddam.
“Babban ci gaba a cikin kula da marasa lafiya tare da hemodialysis da gazawar koda an iyakance su ta hanyar fasahar membrane.Fasahar Membrane ba ta sami ci gaba sosai a cikin ƴan shekarun da suka gabata ba.Babban ci gaban fasaha na membrane yana buƙatar haɓakar dialysis na koda.Abubuwan da za a iya juyewa da zaɓaɓɓu, irin su membrane graphene oxide membrane ultra-bakin ciki wanda aka haɓaka anan, na iya canza yanayin.Matsakaicin bakin ciki maras nauyi ba zai iya gane ƙananan dialyzers kawai ba, har ma da na'urori masu ɗaukar hoto na gaske da kuma sawa, don haka inganta ingancin rayuwa da tsinkayen haƙuri. "James L. McGrath ya ce shi farfesa ne na injiniyan halittu a Jami'ar Rochester kuma mai haɗin gwiwa na sabuwar fasahar siliki mai ƙulli don aikace-aikacen ilimin halitta daban-daban (Nature, 2007).
Cibiyar Nazarin Halittar Halittu ta Kasa (NIBB) ce ta dauki nauyin wannan binciken a karkashin Cibiyar Kiwon Lafiya ta Kasa.Tawagar Dr. Moghaddam ta hada da Dr. Richard P. Rode, jami'in digiri na biyu a UF MAE, Dokta Thomas R. Gaborski (mai binciken babban jami'in), Daniel Ornt, MD (mai binciken co-principal), da Henry C na Sashen Biomedical. Injiniya, Cibiyar Fasaha ta Rochester.Dokta Chung da Hayley N. Miller.
Dr. Moghaddam memba ne na UF Interdisciplinary Microsystems Group kuma yana jagorantar dakin gwaje-gwaje na Nanostructured Energy Systems Laboratory (NESLabs), wanda manufarsa ita ce inganta matakin ilimin nanoengineering na kayan aikin porous da micro/nanoscale watsa physics.Ya haɗa nau'o'in nau'o'in injiniya da kimiyya da yawa don fahimtar ilimin kimiyyar lissafi na micro/nano-sikelin watsawa da haɓaka tsarin tsarawa da tsarin gaba tare da babban aiki da inganci.
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